This file contains statistics and figures from the paper, “Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal organ at Single Cell Resolution” by Max Hills Jr., Limei Ma, Ai Fang, Thelma Chiremba, Seth Malloy, Allison Scott, Anoja Perera, and C. Ron Yu.

The paper can be found here:

Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal organ at Single Cell Resolution

Age Differences

Volcano Plot: P14/P56 Differentially Expressed Genes (DEGs)

Box-Plots: Top Significant Age Genes

GSEA: Significant GO Terms (P14/P56)

---
title: "VNO Atlas Figure S1"
author: "Max Hills"
date: "`r format(Sys.time(), '%d %B, %Y')`"
output:
  html_notebook:
    css: style.css
---

```{r, results='asis'}

cat("<button onclick='history.back()' style='font-size: 20px; background-color: black; color: white; padding: 10px 20px; border: 3px solid yellow; border-radius: 5px;'>Click Here to Return to Previous Page</button>")

```

***  

```{r, engine='css', echo = FALSE}

body {
  font-size: 18px;
}
.nav-pills > li > a {
  color: black; /* Set inactive tab text color to black */
  border: 2px solid black; /* Add black border to inactive tabs */
  border-radius: 4px; /* Optional: Slightly round the corners */
}

.nav-pills > li > a:hover, .nav-pills > li > a:focus {
  background-color: darkgray; /* Set hover background color to a darker gray */
  color: white; /* Set hover text color to white for better contrast */
}

.nav-pills > li.active > a {
  background-color: black; /* Set active tab background color to black */
  color: white; /* Set active tab text color to white */
  border: 3px solid yellow
}

.nav-pills > li.active > a:hover {
  background-color: darkgray; /* Set active tab background color to black */
  color: white; /* Set active tab text color to white */
  border: 3px solid black
}

``` 

>This file contains statistics and figures from the paper, "Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal organ at Single Cell Resolution" by Max Hills Jr., Limei Ma, Ai Fang, Thelma Chiremba, Seth Malloy, Allison Scott, Anoja Perera, and C. Ron Yu.    

The paper can be found here:  

[Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal organ at Single Cell Resolution](https://elifesciences.org/reviewed-preprints/97356#tab-content)

***  

```{r setup, include=FALSE}

# R-Markdown Global Settings  

# Set-up a default image size of 10 X 10 inches. Suppress warning
# and error messages. Hide code.
knitr::opts_chunk$set(echo=FALSE, warning=FALSE, message=FALSE, comment="",
                      error=FALSE, fig.width=15, fig.height=15, cache=FALSE)

```

```{r libraries, include=FALSE}

# Library Loading  

suppressPackageStartupMessages({
  library(kit); library(tidyverse); library(stringr); library(plot3D) 
  library(ggplot2); library(data.table); library(org.Mm.eg.db)
  library(dplyr); library(Seurat); library(DBI); library(cowplot)
  library(Matrix); library(glmGamPoi); library(circlize)
  library(tibble); library(ggpubr); library(svglite); library(ggsignif)
  library(stats); library(vegan); library(scales); library(caret)
  library(patchwork); library(plotly); library(EnhancedVolcano)
  library(openxlsx); library(gridExtra); library(ggrepel)
  library(GeneOverlap); library(biomaRt); library(ggpointdensity)
  library(slingshot); library(tradeSeq); library(SingleCellExperiment)
  library(viridis); library(UpSetR); library(pheatmap); library(msigdbr)
  library(fgsea); library(grid); library(IDPmisc); library(MASS)
  library(Rmisc); library(ggplotify); library(ggpmisc); library(scales)
  library(heatmaply); library(dendextend)
})

```

```{r}

# Global Variables
old_obj_dir <- "/l/Yu/YuLab/Bioinformatics/projects/mhh/sc_VNO/final.seu.objs/"
# The home directory
home_dir <- "/l/Yu/YuLab/Bioinformatics/projects/mhh/sc_VNO/revision/"
# Directory for storing data objects at crucial stages
object_dir <- paste0(home_dir,"objects/")
# Directory for images from the final analysis
image_dir <- paste0(home_dir,"images/")

p14_vs_p56.dge.df <- readRDS(file=paste0(object_dir,"p14_vs_p56.dge.rds"))
all.p14_vs_p56.gene_sets <- readRDS(file=paste0(object_dir,"all.p14_vs_p56.gene_sets.rds"))

#Load Neuronal Lineage Seurat Object  
load(file = paste0(old_obj_dir,"neuron.integrated.postCellID"))
# Rename unknown_mVSN to sVSN
levels(neuron.integrated@active.ident)[levels(neuron.integrated@active.ident)=="unknown_mVSN"] <- "sVSN"
levels(neuron.integrated$cell_type)[levels(neuron.integrated$cell_type)=="unknown_mVSN"] <- "sVSN"

global.vars <- c(ls(),"global.vars")

```

# Age Differences  {.tabset .tabset-pills}  

```{r}

sig.p14_vs_p56.dge.df <- p14_vs_p56.dge.df[p14_vs_p56.dge.df$p_val_adj <= 0.05, ]
# Order the genes by their avg_log2FC
plot.p14_vs_p56.dge <- sig.p14_vs_p56.dge.df[order(abs(sig.p14_vs_p56.dge.df$avg_log2FC),
                                                             decreasing = TRUE), ]

```

## Volcano Plot: P14/P56 Differentially Expressed Genes (DEGs)  

```{r}

age.volcano <- EnhancedVolcano(p14_vs_p56.dge.df,
    lab = rownames(p14_vs_p56.dge.df),
    selectLab = c(rownames(plot.p14_vs_p56.dge)[1:10]),
    axisLabSize = 20,
    x = 'avg_log2FC',
    y = 'p_val_adj',
    title = 'P14 vs P56',
    titleLabSize = 40,
    pCutoff = 0.05,
    FCcutoff = 0.5,
    pointSize = 3.0,
    labSize = 8,
    legendLabSize = 20,
    drawConnectors = TRUE,
    arrowheads=FALSE)

age.volcano

```

```{r}

age.genes.compare <- FetchData(neuron.integrated, 
                               vars=c("age", rownames(plot.p14_vs_p56.dge)[1:16]), 
                               slot = "data")

```

```{r}

age.genes.df <- 
  pivot_longer(data=age.genes.compare,
               cols=2:17,
               names_to="gene",
               values_to="normalized_count")

```

## Box-Plots: Top Significant Age Genes  

```{r}

my_comparisons <- list(c("P14","P56"))

# Custom Palette for Cell Types
age.palette <-wesanderson::wes_palette("Darjeeling1")[4:5]
names(age.palette) <- c("P14","P56")

my_theme <- theme(plot.title = element_text(size=40, hjust=0.5),
                  strip.text.x = element_text(size=32),
                  axis.title = element_text(size=24),
                  axis.text = element_text(size=20),
                  legend.title = element_text(size=24),
                  legend.text = element_text(size=20))

p1 <- ggplot(age.genes.df,aes(x=age,y=normalized_count,fill=age)) + geom_boxplot() +
  facet_wrap(. ~ gene, ncol = 4) +
  scale_fill_manual(values=age.palette) +
  stat_summary(fun.y=mean,geom='point',size=10,colour="black",shape=95,show_guide=FALSE) +
  stat_compare_means(comparisons=my_comparisons,tip.length=0.01,
                     method="wilcox.test",label="p.signif", vjust=0.75) +
  ggtitle("Differentially Expressed Genes by Age") + ylab("Normalized Count (log-scale)") + 
  theme_classic() + my_theme + 
  scale_y_log10()

p1

```

## GSEA: Significant GO Terms (P14/P56)  

```{r, fig.width=30, fig.height=80}

# Define the shapes for the shape_var levels
shape_values <- c(21, 22, 23, 24, 25)  # Point, square, triangle, plus-sign, diamond

# Create the plot
age.go.plot <- ggplot(all.p14_vs_p56.gene_sets, aes(x = NES, y = pathway)) +
  geom_point(aes(size = size, fill = padj, color=padj, shape = Category)) +
  scale_color_gradient(low="hotpink", high="cyan") +
  scale_fill_gradient(low="hotpink", high="cyan") +
  scale_shape_manual(values = shape_values) +
  theme_bw() +
  theme(
    axis.text.y = element_text(size = 24, hjust = 1),  # Increase y-axis text size and adjust for long names
    axis.text.x = element_text(size = 24),             # Increase x-axis text size
    legend.position = "right",                         # Move legend to the right
    plot.margin = margin(1, 2, 1, 1, "cm"),
    plot.title = element_text(hjust = 0.5, size=40),  # Increase margin on the right side
    axis.title = element_text(size=32),
    legend.title = element_text(size=28),
    legend.text = element_text(size=24)
  ) +
  labs(
    title = "P14 vs P56 Gene-Set Enrichment Analysis",
    x = "Normalized Enrichment Score (NES) P14/P56",
    y = "Pathway",
    size = "nGenes",
    fill = "padj",
    shape = "Category"
  ) +
  guides(shape = guide_legend(override.aes = list(size = 5)))

# Print the plot
print(age.go.plot)

```


```{r}

rm(list=ls())
invisible(gc())

```


